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Medical Benefit Drug Medical Necessity Guidelines

The Medical Drug Medical Necessity Guidelines below detail coverage criteria for medical benefit drugs for Harvard Pilgrim Health Care and Tufts Health Plan lines of business. We encourage you to use the drop-down menu to filter applicability by product. We note line of business under the guideline name; however, the policy may not apply to every product in that line of business. Please refer to the policy for product applicability.

Tufts Health Together utilizes MassHealth’s Unified Formulary for pharmacy medications and select medical benefit drugs. For a list of medical benefit medications that utilize MassHealth coverage criteria, refer to the Unified Medical Policies Medical Drug Necessity Guidelines, and for the MassHealth drug coverage and criteria refer to the MassHealth Drug List.

We recommend submitting your prior authorization requests electronically via PromptPA.

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Documents in this collection

Abecma (idecabtagene vicleucel)
Public Plans; Senior Products
Adstiladrin (nadofaragene firadenovec-vncg)
Public Plans; Senior Products
Adzynma (ADAMTS13, recombinantkrhn)
Public Plans; Senior Products
Adzynma (ADAMTS13, recombinantkrhn)
Senior Products
Ajovy (fremanezumab-vfrm)
Public Plans; Senior Products
Altuviiio [antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl]
Public Plans; Senior Products
Amondys45 (casimersen)
Public Plans; Senior Products
Amtagvi (lifileucel)
Public Plans; Senior Products
Amyloidosis Therapies
Public Plans; Senior Products Amvuttra (vutrisiran) and Onpattro (patisiran)
Anktiva (nogapendekin alfa inbakicept-pmln)
Senior Products
Aucatzyl (obecabtagene autoleucel)
Public Plans; Senior Products
Benlysta (belimumab)
Public Plans; Senior Products
Botulinum Toxins
Public Plans; Senior Products; Botox (onabotulinumtoxin A), Daxxify (daxibotulinumtoxinA-lanm), Dysport (abobotulinumtoxin A), Myobloc (rimabotulinumtoxin B), Xeomin (incobotulinumtoxin A)
Breyanzi (lisocabtagene maraleucel)
Public Plans; Senior Products
Carvykti (ciltacabtagene autoleucel)
Public Plans; Senior Products
Casgevy (exagamglogene autotemcel)
Public Plans; Senior Products
Cinryze (C1 esterase inhibitor [Human])
Public Plans; Senior Products
Columvi (glofitamab-gxbm)
Public Plans; Senior Products
Complement Inhibitors
Public Plans; Senior Products; Empaveli (pegcetacoplan), Soliris (eculizumab), Ultomiris (ravulizumab-cwvz), PiaSky
Continuous Glucose Monitoring Systems: Freestyle and Dexcom Products
Public Plans; Senior Products
Cosela (trilaciclib)
Public Plans; Senior Products
Crysvita (burosumab-twza)
Public Plans; Senior Products
Elrexfio (elranatamab-bcmm)
Public Plans; Senior Products
Epkinly (epcoritamab-bysp)
Commercial; Public Plans
Epkinly (epcoritamab-bysp)
Public Plans; Senior Products
Evenity (romosozumab-aqqg)
Public Plans; Senior Products
Exondys51 (eteplirsen)
Public Plans; Senior Products
Factor Products
Public Plans; Senior Products; Advate (Antihemophilic Factor VIII (recombinant)), Adynovate (antihemophilic factor (recombinant), [PEGylated]), Afstyla (antihemophilic factor (recombinant)), Alphanate (antihemophilic factor/von Willebrand factor complex [human]), Alphanine (Coagulation Factor IX (human)), Alprolix (Coagulation Factor IX (recombinant)), Benefix (Coagulation Factor IX (recombinant)), Coagadex (Coagulation Factor X (human)), Corifact (factor xiii concentrate (human)), Eloctate (antihemophilic factor (recombinant)), Espercot (antihemophilic factor (recombinant), glycopegylated-exel), Feiba NF (Anti-inhibitor coagulant complex), Hemofil M (antihemophilic factor (human)), Humate- P (Antihemophilic Factor/von Willebrand Factor Complex (Human)), Idelvion (Coagulation Factor IX (recombinant), albumin fusion protein), Ixinity (coagulation factor ix (recombinant)), Jivi (Antihemophilic Factor VIII (recombinant), PEGylated-aucl), Kovaltry (Antihemophilic, Factor VIII (recombinant)), Koate DVI (Antihemophilic Factor VIII (human)), Monoclate- P (antihemophilic factor (human)), Mononine (Coagulation Factor IX (Human)), Novoseven (coagulation factor viia (recombinant)), Novoeight (Antihemophilic Factor VIII (recombinant)), Nuwiq (Antihemophilic Factor VIII (recombinant)), Obizur (Antihemophilic Factor VIII (recombinant)), Recombinate (Antihemophilic Factor VIII (recombinant)), Rebinyn (coagulation factor ix (recombinant)), Rixubis (Coagulation Factor IX (recombinant)), Profilnine SD (factor ix complex), Sevenfact (coagulation factor viia (recombinant)-jncw), Tretten (Coagulation Factor XIII A-Subunit (Recombinant)), Wilate (Von Willebrand Factor/Coagulation Factor VIII complex), Vonvendi (Von Willebrand Factor (recombinant)), Xyntha (Antihemophilic Factor (recombinant))
Givlaari (givosiran)
Public Plans; Senior Products
Haegarda (C1 Esterase Inhibitor Subcutaneous [Human])
Public Plans; Senior Products

Oncology Medical Management

If you are utilizing a medical drug for oncology purposes for a Harvard Pilgrim Health Care Commercial or Stride (HMO/ HMO-POS) Medicare Advantage member, prior authorization is necessary through OncoHealth. For more information, please refer to the OncoHealth link on the Medical Necessity Guidelines page and the Harvard Pilgrim vendor programs resource page.

 

Medical Drugs Available through Specialty Pharmacies

You can access a number of medical benefit drugs through specialty pharmacies. Options are detailed in the “Office-Administered Medical Drugs” policies found on this page. There are 3 versions of this policy, based on product: for Harvard Pilgrim Health Care commercial, Tufts Health Plan Commercial and Tufts Medicare Preferred, and Tufts Health Direct.

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