Back to Insights and Updates for ProvidersSeptember 2025

New laboratory Payment Policies

Harvard Pilgrim Health Care Commercial

As you know, medical costs have been rising sharply. One area of focus is laboratory services, which account for more than $82 billion annually in the United States. Point32Health is committed to ensuring members have access to medically necessary laboratory services while implementing policies that support appropriate utilization and affordability of care.

As part of these efforts, we are implementing a new laboratory benefit management program for Harvard Pilgrim Health Care Commercial products, effective for dates of service beginning Nov. 1, 2025.*

As of this effective date, we will implement the following new Payment Policies and utilize automated claims edits (post-service, pre-payment) to ensure consistency with the guidelines for laboratory services, tests, and procedures performed in office, hospital outpatient, and independent laboratory locations. Laboratory services provided in emergency rooms, hospital observation, and hospital inpatient settings are excluded from this program.

New Payment Policies for Harvard Pilgrim Health Care Commercial*
  • Cervical Cancer Screening
  • Prostate Biopsies
  • Diagnostic Testing of Iron Homeostasis & Metabolism
  • Immunohistochemistry
  • Biomarker Testing for Autoimmune Rheumatic Disease
  • Hepatitis C
  • Pediatric Preventative Screening
  • Helicobacter Pylori Testing
  • Biochemical Markers of Alzheimers Disease and Dementia
  • Bone Turnover Markers Testing
  • Diagnosis of Vaginitis including Multi-target PCR Testing
  • Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant Testing
  • Therapeutic Drug Monitoring for 5-Fluorouracil
  • Identification of Micro-organisms by Nucleic Probes
  • Intracellular Micronutrient Analysis
  • Immunopharmacologic Monitoring of Therapeutic Serum Antibodies
  • Serum Marker Panels for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver Disease
  • Oral Screening Lesion Identification Systems and Genetic Testing
  • Plasma HIV 1 RNA Quantification for HIV-1 Infection
  • Salivary Hormone Testing
  • Biomarker Testing for Multiple Sclerosis and Related Neurologic Diseases
  • Urinary Tumor Markers for Bladder Cancer
  • Testing of Homocysteine Metabolism-Related Conditions
  • Cardiac Biomarkers for Myocardial Infarction
  • Pancreatic Enzyme Testing for Acute Pancreatitis
  • General Inflammation Testing
  • Diagnostic Testing of Most Common Sexually Transmitted Infections
  • Hemolytic Streptococcus Testing
  • Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing
  • Gamma-glutamyl Transferase
  • Colorectal Cancer Screening
  • Hemoglobin A1c Diabetes Mellitus Testing
  • Prostate Specific Antigen (PSA) Testing
  • Testosterone Testing
  • Flow Cytometry
  • Prenatal Screening (Nongenetic)
  • Venous and Arterial Thrombosis Risk Testing
  • Celiac Disease
  • Thyroid Disease Testing
  • Cardiovascular Disease Risk Assessment
  • Diagnosis and Management of Idiopathic Environmental Intolerance
  • Epithelial Cell Cytology in Breast Cancer Risk Assessment
  • Gamma Interferon Blood Test for Dx of Latent Tuberculosis
  • Testing For Alpha-1 Antitrypsin Deficiency
  • Immune Cell Function Assay
  • Invitro Chemoresistance and Chemosensitivities Assays
  • Measurement of Thromboxane Metabolites for ASA Resistance
  • Nerve Fiber Density Testing
  • Pharmacogenomic and Metabolite Markers for Thiopurines
  • Diagnostic Testing of Influenza
  • Serum Antibodies for the Diagnosis of Inflammatory Bowel Disease
  • Serum Tumor Markers for Malignancies
  • Evaluation of Dry Eyes
  • Pathogen Panel Testing
  • Serum Testing for Evidence of Mild Traumatic Brain Injury
  • Folate Testing
  • Urine Culture Testing for Bacteria
  • Mosquito- and Tick-Related Infections
  • Avalon Laboratory Procedures Reimbursement Policy
  • Onychomycosis Testing
  • Coronavirus Testing in the Outpatient Setting

To access these policies and review details, visit the Payment Policy section of our Provider website. For ease of identification, all the policies listed above begin with “Laboratory” and the name shown on our Payment Policies page (for example, “Laboratory: Colorectal Cancer Screening” and “Laboratory: Hepatitis C). These evidence-based policies are aligned with the latest scientific research to determine the appropriateness of lab testing.

We encourage ordering providers and laboratories that utilize requisition forms and panels to review the new Payment Policies and adjust forms as needed to help avoid ordering and conducting tests that would not be covered.

*This effective date does not apply for Maine providers, as we will announce the program for Maine providers in the October issue of the provider newsletter, consistent with Maine legislative requirements.